Simulation of the Adenylic acid system and lactate concentration during isokinetic force loads
Oral Presentation
Keywords:
simulation, force load, anaerobic power, adenyl acidAbstract
DOI: https://doi.org/10.30472/aesa-conf.v7i1
Energy expenditure during endurance exercise is fairly well known and studied. However, for short duration exercise (such as maximal force exercise) the knowledge is very limited and not measurable during exercise. Based on bio-chemical models, the physiological kinetic of energetic substrates of anaerobic metabolism can be estimated (Mader, 2002). The aim of this study was to simulate the kinetic of the adenylic acid system and lactate concentration during maximal force load.
10 trained men (25.1±4.5 years, 182.6±7.2 cm, 82.4±10.9 kg, training 7.9±3.5 hours per week) were tested for their O2max (Ramp-test) (Craig et al., 2000). Furthermore, 10 single-leg reps were performed using isokinetic strength testing (knee ex/flex, 150°/s, load time 17.5±0.4 s) at maximal power. Capillary blood samples (20µl) were taken before, immediately after and up to the ninth post-load minute. The O2max, power curve, Lamax, active muscle mass (16%) and body mass were used as input parameters for the simulation.
The adenylic acid system showed a physiological course in the simulation based on the power curve of the maximum force loading. The pre-post-concentrations showed significant changes in Creatinphosphate (PCr): t0 20.0±0.002 mmol*kg-1; t17 16.22±0.89 mmol*kg-1 (p<0.001; depletion of 19.9%), Adenosine-di-Phosphate (ADP): t0: 0.005±0.0 mmol*kg-1; t17 0.016±0.003 mmol*kg-1 (p=0.005; increase of 313.8 %), Adenosine-mono-Phosphate (AMP): t0: 4.38-6 ±8.06-8 mmol*kg-1; t17: 4.47-5±1.58-5 mmol*kg-1 (p=0.005; increase of 1021.6%) and a very low depletion in Adenosine-tri-Phosphate (ATP): t0: 5.99±0.0 mmol*kg-1; t17 5.98±0.003 mmol*kg-1 (p=0.005; depletion of 0.19%). The measured lactate concentration at the end of the 10 repetitions amounted 1.04±0.47 mmol*l-1, the simulated lactate concentration was 0.99±0.0006 mmol*l-1. The difference between simulated and measured lactate concentration was 0.0485±0.47 mmol*l-1 (p=0.752) with a standard error by 0.44 mmol*l-1. Although the simulation of the adenyl acid system indicates a plausible physiological course, the residuals of the linear regression in the lactate concentration appear too high.
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