Effect of TRX with blood flow restriction on IGF-1, protein synthesis, and function in females

TRX WITH BFR IN ACTIVE FEMALES

Abstract

^{Purpose: the study aims to evaluate the effect of high-intensity TRX resistance training with blood flow restriction (BFR) on IGF-1, protein synthesis, muscle volume, and function of active girls. Method: This is a Quasi-Experimental Design. The subjects were 45 females. They were accessibly selected as a sample and divided into three groups, the high-intensity TRX resistance training group (TRX=15), the TRX resistance with blood flow restriction group (TRXBFR=15), and the control group (C=15) at random. TRX and TRXBFR groups performed TRX training for 8 weeks and 3 sessions per week. The TRXBFR group applied a rubber cuff at the proximal end of the thigh and the Borg Pressure Perception Index (7-10 scale) determined blood flow restriction. The training protocol included a general warm-up, the main training program, and a cool-down. The measurements include; protein synthesis by urinary nitrogen (Autlab, Ames, and Rame); Insulin-Like Growth Factor 1 (IGF-1, CK-MM kit), and creatine kinase enzyme, (ELISA kite). Lean body mass (Lee formula); muscle strength (dynamometer); peak and mean power (Wingate bike test). ANCOVA and Bonferroni post hoc tests determined within and between-group changes. Results: The results showed that eight weeks of TRX training with and without the blood flow restriction increased significantly. Including; IGF-1, Lean body mass, muscle strength, peak anaerobic power, mean anaerobic power, creatine kinase, and protein synthesis in the TRXBFR group compared to TRX and C groups (P<0.05). Conclusion: It seems BFR along with resistance TRX exercise is a convenient method to improve physical fitness and resistance exercise.}